Ireland head coach Andy Farrell has made three changes to his side for Saturday's Six Nations clash with Scotland.
Jack Conan, Mack Hansen and Iain Henderson have all been handed starting roles.
Peter O'Mahony drops to the bench, with Andrew Conway missing out due to a knee problem.
James Ryan continues to go through the return to play protocols after sustaining a head injury against England.
Ireland: Hugo Keenan; Mack Hansen, Garry Ringrose, Bundee Aki, James Lowe; Johnny Sexton (capt), Jamison Gibson-Park; Cian Healy, Dan Sheehan, Tadhg Furlong; Tadhg Beirne, Iain Henderson; Caelan Doris, Josh van der Flier, Jack Conan.
Replacements: Rob Herring, Dave Kilcoyne, Finlay Bealham, Kieran Treadwell, Peter O'Mahony, Conor Murray, Joey Carbery, Robbie Henshaw.